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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL4
All Species:
9.09
Human Site:
T684
Identified Species:
25
UniProt:
O94761
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94761
NP_004251.2
1208
133077
T684
S
V
S
M
D
R
D
T
D
Q
A
L
L
T
L
Chimpanzee
Pan troglodytes
XP_520023
1208
133141
T684
S
V
S
M
D
R
D
T
D
Q
A
L
L
T
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539222
1209
131690
L656
A
R
D
V
A
R
H
L
G
V
A
E
E
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q75NR7
1216
135105
S706
S
V
S
M
D
R
D
S
D
Q
A
L
V
T
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
L652
A
L
A
Y
H
A
G
L
T
D
S
N
R
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920631
1380
154059
K847
S
V
S
M
D
R
D
K
D
Q
A
L
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393782
1284
145763
R799
T
I
S
K
D
E
N
R
D
Q
A
L
I
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187631
1990
223246
R1192
S
A
S
K
D
L
A
R
E
R
A
L
I
E
L
Poplar Tree
Populus trichocarpa
XP_002315627
901
101082
E478
I
K
S
P
P
F
V
E
L
Q
S
I
I
I
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
57.8
N.A.
65.9
N.A.
N.A.
N.A.
21.1
N.A.
41.2
N.A.
N.A.
33.2
N.A.
27
Protein Similarity:
100
99.2
N.A.
66.7
N.A.
75
N.A.
N.A.
N.A.
35.4
N.A.
56.5
N.A.
N.A.
51.3
N.A.
39.3
P-Site Identity:
100
100
N.A.
13.3
N.A.
86.6
N.A.
N.A.
N.A.
6.6
N.A.
80
N.A.
N.A.
46.6
N.A.
40
P-Site Similarity:
100
100
N.A.
33.3
N.A.
100
N.A.
N.A.
N.A.
33.3
N.A.
93.3
N.A.
N.A.
73.3
N.A.
60
Percent
Protein Identity:
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
12
0
12
12
12
0
0
0
78
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
67
0
45
0
56
12
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
12
0
12
12
0
0
12
12
12
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
0
0
0
0
0
0
0
12
34
12
0
% I
% Lys:
0
12
0
23
0
0
0
12
0
0
0
0
0
12
0
% K
% Leu:
0
12
0
0
0
12
0
23
12
0
0
67
23
12
78
% L
% Met:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
56
0
23
0
12
0
0
12
0
0
% R
% Ser:
56
0
78
0
0
0
0
12
0
0
23
0
0
12
0
% S
% Thr:
12
0
0
0
0
0
0
23
12
0
0
0
0
34
0
% T
% Val:
0
45
0
12
0
0
12
0
0
12
0
0
23
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _